We're in constant pursuit of breakthroughs that improve patients' lives. We drive innovation each day to make the world a healthier place. It was Charles Pfizer's initial vision, and it remains true today. Studies show what intuition tells us: that purpose-driven companies deliver better results, are more creative, draw and keep the best talent, and know how to maximize the power of those people. Pfizer's purpose—Breakthroughs that transform patients' lives—drives everything we do and demonstrates our passion for expanding our legacy as one of the most significant contributors of good to the world. Each word in our purpose has meaning and embodies the value we work to bring to patients and society. Our purpose ensures that patients remain at the centre of all we do. We fulfill our purpose by finding the best science in the world, partnering with others in the healthcare system to enhance access to our medicines, employing digital technologies to improve our drug discovery and development, as well as patient outcomes, and driving the conversation to campaign for pro-innovation/pro-patient policies. Every determination we make, and every step we take is done with the patient in mind—and to create an environment where breakthroughs can prosper.

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We're in tireless pursuit of breakthroughs that improve patients' lives. We drive innovation daily to make the world a healthier place. This was Charles Pfizer's initial vision, and it holds true today. Evidence confirms what we instinctively know: that purpose-driven companies achieve more, are more creative, recruit and maintain the best talent, and know how to maximize the power of those individuals. Pfizer's purpose—Breakthroughs that transform patients' lives—fuels everything we do and reflects our passion for expanding our legacy as one of the most significant contributors of good to the world. Each word in our purpose has meaning and represents the value we aim to bring to patients and society. Our purpose makes certain that patients stay at the centre of all we do. We fulfill our purpose by sourcing the best science in the world, collaborating with others in the healthcare system to improve access to our medicines, employing digital technologies to enhance our drug discovery and development, as well as patient outcomes, and leading the conversation to advocate for pro-innovation/pro-patient policies. Every determination we make, and every move we take is done with the patient in mind—and to foster an environment where breakthroughs can flourish.

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Wachstumshormon (Human Growth Hormone, HGH) ist ein peptidisches Hormon, das von der Hirnanhangdrüse produziert wird. Es spielt eine entscheidende Rolle bei der Regulation von Körpergröße, Stoffwechsel und Muskelaufbau. Im Folgenden werden die Hauptwirkungen, medizinische Indikationen sowie mögliche Nebenwirkungen von HGH erläutert.





Physiologische Wirkung



Prozess Wirkung des HGH


Knochenwachstum Stimuliert das Wachstum von Knochen und Knorpel durch Förderung der Zellteilung in Wachstumsfugen.


Muskelaufbau Erhöht die Proteinsynthese, was zu einer Zunahme an Muskelmasse führt.


Fettstoffwechsel Fördert Lipolyse (Abbau von Fettdepots) und reduziert gleichzeitig die Fettspeicherung.


Glukosestoffwechsel Hemmt die Insulinwirkung leicht, wodurch der Blutzuckerspiegel erhöht wird.


Immunsystem Unterstützt die Regeneration von Geweben und kann das Immunsystem stärken.





Medizinische Indikationen



Wachstumsstörungen bei Kindern


- Mangel an HGH (Idiopathisches Wachstumshormonmangel).

- Syndrom des Zellstoffwechseldefekts (Laron-Syndrom).





Verluste durch altersbedingte HGH-Reduktion


- Behandlung von Muskelschwund und Knochendichteverlust bei älteren Erwachsenen.



Gewichtsmanagement bei bestimmten Erkrankungen


- Patienten mit HIV/AIDS, die an erheblichem Gewichtsverlust leiden.




Körperliche Rehabilitation


- Nach Operationen oder schweren Verletzungen zur Beschleunigung der Heilung.



Dosierung und Verabreichungsform



Patientengruppe Typische Dosis Verabreichungsweg


Kinder mit HGH-Mangel 0,05–0,1 µg/kg/Tag Subkutane Injektion (täglich oder zweimal pro Woche)


Erwachsene bei Gewichtsverlust 1–3 µg/kg/Tag Subkutane Injektion (nach Bedarf)


Senioren für Knochendichte 1–2 µg/kg/Tag Subkutane Injektion (einmal täglich)



Die genaue Dosierung wird individuell angepasst und sollte unter ärztlicher Aufsicht erfolgen. Die Behandlung dauert in der Regel mehrere Monate bis Jahre.





Nebenwirkungen



Symptom Häufigkeit Maßnahmen


Ödeme, Schwellungen Bis zu 30 % Flüssigkeitsreduktion, niedrigere Dosis


Gelenkschmerzen 10–20 % Schmerzmittel, physiotherapeutische Unterstützung


Hyperglykämie 5–15 % Blutzuckerkontrolle, ggf. Insulin anpassen


Akromegalie (bei Überdosierung)

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