We're in tireless pursuit of breakthroughs that improve patients' lives. We create innovations each day to make the world a more healthy place. This was Charles Pfizer's initial vision, and it holds true today. Evidence confirms what we instinctively know: that purpose-driven companies perform better, are more creative, recruit and maintain the best people, and know how to unleash the power of those individuals. Pfizer's purpose—Breakthroughs that transform patients' lives—drives everything we do and reflects our passion for expanding our legacy as one of the most significant contributors of good to the world. Each word in our purpose has importance and embodies the value we work to bring to patients and society. Our purpose makes certain that patients continue to be at the centre of all we do. We embody our purpose by finding the best science in the world, working with others in the healthcare system to enhance access to our medicines, employing digital technologies to advance our drug discovery and development, as well as patient outcomes, and spearheading the conversation to campaign for pro-innovation/pro-patient policies. Every determination we make, and every step we take is done with the patient in mind—and to create an environment where breakthroughs can thrive.

Refugio Candler, 20 years
We're in relentless pursuit of breakthroughs that transform patients' lives. We drive innovation every day to make the world a more healthy place. This was Charles Pfizer's initial vision, and it remains true today. Studies show what intuition tells us: that purpose-driven companies perform better, are more innovative, draw and keep the best people, and know how to harness the power of those team members. Pfizer's purpose—Breakthroughs that change patients' lives—drives everything we do and demonstrates our passion for growing our legacy as one of the most important contributors of good to the world. Each word in our purpose has meaning and represents the value we strive to bring to patients and society. Our purpose makes certain that patients stay at the centre of all we do. We fulfill our purpose by seeking the best science in the world, partnering with others in the healthcare system to enhance access to our medicines, utilizing digital technologies to improve our drug discovery and development, as well as patient outcomes, and driving the conversation to campaign for pro-innovation/pro-patient policies. Every determination we make, and every move we take is done with the patient in mind—and to nurture an environment where breakthroughs can thrive.

Alphonso Zuniga, 20 years
We are in constant pursuit of breakthroughs that change patients' lives. We create innovations daily to make the world a more healthy place. This was Charles Pfizer's original vision, and it still holds true today. Evidence confirms what intuition tells us: that purpose-driven companies deliver better results, are more inventive, recruit and maintain the best talent, and know how to maximize the power of those team members. Pfizer's purpose—Breakthroughs that change patients' lives—powers everything we do and demonstrates our passion for expanding our legacy as one of the most meaningful contributors of good to the world. Each word in our purpose has meaning and represents the value we work to bring to patients and society. Our purpose guarantees that patients continue to be at the centre of all we do. We live our purpose by sourcing the best science in the world, working with others in the healthcare system to increase access to our medicines, utilizing digital technologies to enhance our drug discovery and development, as well as patient outcomes, and spearheading the conversation to advocate for pro-innovation/pro-patient policies. Every determination we make, and every move we take is done with the patient in mind—and to create an environment where breakthroughs can flourish.

Sabrina Wannemaker, 20 years

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Was ist Somatropin?



Somatropin ist ein rekombinantes menschliches Wachstumshormon (hGH), das im Labor aus gentechnisch veränderten Bakterien oder Hefezellen hergestellt wird. Es entspricht dem natürlichen Hormon, das die Hypophyse produziert, und wird in der Medizin zur Behandlung von Wachstumsstörungen sowie einiger Erkrankungen eingesetzt, bei denen ein Mangel an Wachstumshormonen vorliegt.






Anwendungsgebiete



Indikation Zielgruppe Typische Dosierung


Kinder mit primärem Wachstumshormonmangel Kinder unter 18 Jahren 0,03–0,05 mg/kg Körpergewicht pro Woche (in 2-3 Injektionen)


Körperliche Wachstumsverzögerung bei chronischen Erkrankungen (z. B. Mukoviszidose, Chronische Nierenerkrankung) Kinder und Jugendliche Ähnlich wie oben, ggf. angepasst an Körpergewicht


Altersbedingter HGH-Mangel Erwachsene >50 Jahre 0,25–0,5 mg/Tag (injektionär oder subkutan)


Körperliche Regeneration nach Operationen Sportler, Patienten mit schwerem Gewichtsverlust Dosierung variiert stark; häufig 1–2 mg/Tag für kurze Zeiträume



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Wirkungsweise




Stimulation des Zellwachstums: Somatropin bindet an spezifische Rezeptoren auf Zellen und aktiviert Signalwege, die Zellteilung und Proteinsynthese fördern.


Anstieg von IGF-1 (Insulinähnlicher Wachstumsfaktor 1): Das Hormon regt die Leber an, IGF-1 zu produzieren, welches wiederum das Knochenwachstum, die Muskelmasse und die Fettverteilung beeinflusst.


Metabolische Effekte: Erhöhung des Lipolyseprozesses (Fettabbau), Verbesserung der Glukosemetabolismuskontrolle und Unterstützung der Eiweißansammlung im Körper.









Häufige Nebenwirkungen



Symptom Häufigkeit Kurzfristig / Langfristig


Ödeme (Schwellungen, vor allem an Händen/Knöcheln) bis zu 30 % Kurz- und langfristig


Gelenk- und Muskelschmerzen ~20 % Kurzfristig


Hyperglykämie / Hypoglykämie

Georgina Standish, 20 years

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